Monge VetSolution Hepatic Feline, 1.5 kg
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4.08/5 (442)
Monge Vetsolution Hepatic Feline este o hrana dietetica completa destinata pisicilor cu insuficienta hepatica cronica, fiind conceputa pentru sustinerea functiei hepatice. Monge Vetsolution Hepatic Feline contine Super Oxid Dismutaza (SOD) pentru prevenirea stesului oxidativ, Sylibum marianum cu proprietati antiinflamatoare si anti-fibrotice, Xilo-Oligozaharide (XOS) pentru protejarea microflorei intestinale, formula furnizand totodata proteine de inalta calitate, un nivel moderat de proteine si un nivel ridicat de acizi grasi esentiali.
Silbina, componenta activa din extractul de armurariu, din Monge Vetsolution Hepatic Feline, prezinta numeroase efecte benefice asupra functiei hepatice. In hepatocite, silibina scindeaza radicalii liberi, inhiba peroxidarea lipidelor si contracareaza inflamatia si fibroza hepatica.Proprietatile antiinflamatorii ale silibinei sunt cauzate de efectele mediate de ADN-ul / ARN-ul nuclear. Un rol important in declansarea fibrozei hepatice il are transformarea celulelor stelate hepatice in miofibroblaste, care este limitata de silibina prin intreruperea semnalizarii celulare. Silibina scade sinteza ADN-ului celulelor stelate, proliferarea si migratia acestora si limiteaza productia tesutului fibros.Silibina inhiba de asemenea absorbtia hepatocitara a altor toxine de catre polipeptidele membranare de legare a sarurilor biliare. Farmacocinetica silibinei legate de fosfatidilcolina a fost recent stabilita la pisici, demonstrand ca biodisponibilitatea orala este marita cu aproximativ 7%, fiind datorata in parte capacitatii limitate de glucuronidare la aceasta specie. Silibina ramane in mare masura limitata la recircularea enterohepatica, iar concentratiile biliare sunt de aproape 100 de ori mai mari comparativ cu concentratiile plasmatice. Efectul hepatoprotector al silibinei din Monge Vetsolution Hepatic stimuleaza sinteza proteinelor, necesara regenerarii hepatice.
- Categorie: Diete veterinare pisici
- Brand: Monge
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